This finding is encouraging. However, if you are pregnant or want to have a baby, talk to your doctor. Clinical trials of Isentress have not included large numbers of people who are 65 years or older so its effectiveness and safety in this population is not known.
In clinical trials, Isentress was well tolerated, generally safe and effective. However, as with any treatment, there were side effects but these were usually of mild to moderate intensity and temporary, such as the following:.
Note that the HIV-positive people who are typically enrolled in pivotal clinical trials of HIV treatments, including Isentress, are generally young and healthy. Once a drug is approved and more widely available, it gets used by populations who are not usually in pivotal clinical trials. These people may be older and may have other health issues—such as cardiovascular disease, liver injury, kidney injury, type 2 diabetes, anxiety, depression, and substance use—that require medications or that cause symptoms.
As a result, their experience of side effects may be different from those reported in pivotal clinical trials. Anxiety and depression are relatively common in HIV-positive people regardless of whether they are on treatment or the type of treatment that they take.
If you are taking Isentress and think that you may have developed anxiety or depression, speak to your doctor right away. Your doctor can help determine if you have anxiety or depression and if there is any relationship between them and the medicines that you are taking.
Symptoms of anxiety and depression can include the following:. Such interference is called a drug interaction. Some drugs can reduce the levels of Isentress in your blood. This can make Isentress less effective and lead to treatment failure, possibly reducing your future treatment options.
Other drugs can raise the levels of Isentress in your blood, resulting in enhanced side effects or new side effects. Therefore it is important to disclose to your doctor and pharmacist all the supplements, drugs, and herbs you are taking.
This factsheet is not comprehensive and only lists some of the potential and actual drug interactions with Isentress. Speak to your pharmacist to find out more about drug interactions with Isentress. Some antacids contain calcium while others contain magnesium or aluminum; some contain combinations of these metals. Merck warns that antacids containing aluminum or magnesium should not be taken with Isentress while antacids that contain calcium can be taken with Isentress.
If you need to take antacids, speak to your pharmacist about ones that are safe for you to use. Remind your pharmacist that you are taking Isentress. Over time, as new copies of HIV are made in the body, the virus changes its structure.
These changes, called mutations, can cause HIV to resist the effects of anti-HIV drugs, which means those drugs will no longer work for you. To reduce the risk of developing drug resistance, all anti-HIV drugs should be taken every day exactly as prescribed and directed.
If doses are delayed, missed or not taken as prescribed, the level of Isentress in the blood may fall too low. If this happens, the HIV in your body can become resistant to Isentress and possibly other drugs you are taking.
If you find you are having problems taking your medications as directed, speak to your doctor, nurse or pharmacist about this. They can find ways to help you. When HIV becomes resistant to one drug in a class, it sometimes becomes resistant to other drugs in that class. This is called cross-resistance. Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule.
Do not take two tablets of raltegravir at the same time to make up for a missed dose. Raltegravir may cause other side effects. Call your doctor if you have any unusual problems while taking this medication. Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture not in the bathroom.
Do not remove the desiccant small packet included with the tablets to absorb moisture from your bottle. It is important to keep all medication out of sight and reach of children as many containers such as weekly pill minders and those for eye drops, creams, patches, and inhalers are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location — one that is up and away and out of their sight and reach.
Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Keep all appointments with your doctor and the laboratory while taking raltegravir. Your doctor will order certain lab tests to check your body's response to raltegravir. It is important for you to keep a written list of all of the prescription and nonprescription over-the-counter medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements.
You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
Raltegravir pronounced as ral teg' ra veer. Why is this medication prescribed? How should this medicine be used? Other uses for this medicine What special precautions should I follow? What special dietary instructions should I follow?
What should I do if I forget a dose? Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with raltegravir. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Important : although it is common for people taking raltegravir to develop a skin rash, a severe rash with blisters may be a sign of a more serious allergic-type reaction. Let your doctor know straightaway if you develop the following:. If you experience any other symptoms which you think may be due to raltegravir, speak with your doctor or pharmacist for further advice.
Never take more than the prescribed dose. If you suspect that you or someone else might have taken an overdose of this medicine, go to the accident and emergency department of your local hospital at once. Take the container with you, even if it is empty. This medicine is for you. Never give it to other people even if their condition appears to be the same as yours. Do not keep out-of-date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you.
Dated October Dated May I have been having a few problems with my vagina. Recently it has been getting very dry and starts to itch. When it does this it gets irritated and then feels like there are blisters on my vagina Disclaimer: This article is for information only and should not be used for the diagnosis or treatment of medical conditions. Egton Medical Information Systems Limited has used all reasonable care in compiling the information but make no warranty as to its accuracy.
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