Immune System Diseases. Powering Discoveries to Rebalance the Immune System BRI is powering discoveries to prevent and treat immune system diseases and rebalance the immune system. Autoimmune Diseases.
Infectious diseases are caused by pathogens "germs" including viruses, bacteria, fungi and parasites, and are ranked as the second leading cause of death worldwide by the World Health Organization.
Type 1 Diabetes. Multiple Sclerosis. Rheumatoid Arthritis. Celiac Disease. Relapsing Polychondritis. Liver Disease. Heart Disease.
Learn about melanoma of the eye, how it can be detected and its treatments. Learn about gallbladder cancer, a rare cancer that can develop in the gallbladder, a small organ beneath the liver. Learn more about germ cell tumours, a type of cancer that can develop in the cells that produce eggs or sperm. Learn about the symptoms and treatments of cancers that can develop in the head and neck.
Learn about Hodgkin lymphoma, an uncommon cancer that develops in the lymphatic system. These are passed on through your parents' gene and cover a wide range of cardiac conditions. Learn about Kaposi's sarcoma, a rare type of cancer that affects the skin and internal organs. Learn about the symptoms and treatments of kidney cancer, the eighth most common cancer in adults in the UK.
Information is about a condition called Langerhans cell histiocytosis which is classed as a type of cancer. Information on liver tumours in children including symptoms and treatments. Learn about the symptoms and treatments of lung cancer, one of the most common cancer types in the UK.
Learn about mesothelioma, a type of cancer that develops in the outer lining of some of the body's organs. Learn about the symptoms and treatments of mouth cancer, also known as oral cancer. Learn about the symptoms and treatments of multiple myeloma, a type of bone cancer. Learn about symptoms and treatments of cancer of the nasal cavity and sinuses. Learn about nasopharyngeal cancer, a rare type that affects a part of the throat, nose and mouth.
Learn about neuroblastoma, a rare cancer that mostly affects children and young people. Learn about symptoms and treatments of neuroendocrine tumours, a wide-ranging and rare group of tumours. Learn about non-Hodgkin lymphoma, a cancer that can develop in part of the circulatory system. Information on non-Hodgkin lymphoma, a type of blood cancer that can be found in children.
Learn about oesophageal cancer, a cancer that can develop in the tube that carries food from the throat to the stomach. Information on symptoms and treatments of osteosarcoma, a type of bone cancer. Information on cancer of the ovaries, part of the female reproductive system. Learn about Paget's disease of the nipple, a rare type of breast cancer. As the world's population grows, and the proportion of elderly people increases, the number of people living in suboptimum health is set to rise rapidly over coming decades, warn the authors.
The findings come from the largest and most detailed analysis to quantify levels, patterns, and trends in ill health and disability around the world between and In the past 23 years, the leading causes of health loss have hardly changed. Low back pain, depression, iron-deficiency anemia, neck pain, and age-related hearing loss resulted in the largest overall health loss worldwide measured in terms of YLD -- Years Lived with Disability -- ie, time spent in less than optimum health [2] in both and In , musculoskeletal disorders ie, mainly low back pain, neck pain, and arthritis and mental and substance abuse disorders predominantly depression, anxiety, and drug and alcohol use disorders accounted for almost half of all health loss worldwide.
Importantly, rates of disability are declining much more slowly than death rates. The GBD Disease and Injury Incidence and Prevalence Collaborators analysed 35, sources of information on disease and injury from countries between and to reveal the substantial toll of disabling disorders and the overall burden on health systems from acute and chronic diseases and injuries, as well as health consequences sequelae that result from one or more of these disorders.
In , low back pain and major depression ranked among the top ten greatest contributors to disability in every country, causing more health loss than diabetes, chronic obstructive pulmonary disease, and asthma combined. Worldwide, the number of individuals with several illnesses rapidly increased both with age and in absolute terms between and The main drivers of increases in the number of years lived with disability were musculoskeletal, mental, and substance abuse disorders, neurological disorders, and chronic respiratory conditions.
In central Europe, falls cause a disproportionate amount of disability and health burden, ranking as the second leading cause of disability in 11 of 13 countries.
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